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Post by Falcon on Oct 30, 2021 7:44:16 GMT
Testing of dialysate shows all the electrolytes in desired range, except cl- which is coming out to he less. What could be the possible cause of this(excluding any error on part of testing equipment).
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Post by Chuck Weddle on Oct 30, 2021 11:22:31 GMT
Short answer is: If the electrolytes are fine, don't worry about the chloride. Chloride is not an electrolyte. Explanation: There is a +/- for EVERYTHING and every test. I don't know what the variances are for each item but when you add them all up in various combinations the POSSIBLE different results are mind numbing: Example:- Actual amount of item in product +/- 2%
- Calibration of manufacturer equipment +/- 2%
- Calibration of the reference equipment for machine calibration +/- 2%
- Dialysis machine calibration +/- 2%
- Calibration of lab equipment +/- 2%
And I'm sure there are a number of other things also, not to mention sample stability.
Here, we don't measure chloride (at least our lab doesn't). Something to understand about chloride: It does not exist as an element by itself, only as part of a compound such as Sodium Chloride (NaCl), Potassium Chloride (KCl), etc.. If the chloride were to disassociate, it becomes chlorine. Chlorine is very unstable in solution and will degas quickly. Could this be the reason? I don't know.
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Post by Falcon on Oct 30, 2021 19:30:54 GMT
Short answer is: If the electrolytes are fine, don't worry about the chloride. Chloride is not an electrolyte. Explanation: There is a +/- for EVERYTHING and every test. I don't know what the variances are for each item but when you add them all up in various combinations the POSSIBLE different results are mind numbing: Example:- Actual amount of item in product +/- 2%
- Calibration of manufacturer equipment +/- 2%
- Calibration of the reference equipment for machine calibration +/- 2%
- Dialysis machine calibration +/- 2%
- Calibration of lab equipment +/- 2%
And I'm sure there are a number of other things also, not to mention sample stability.
Here, we don't measure chloride (at least our lab doesn't). Something to understand about chloride: It does not exist as an element by itself, only as part of a compound such as Sodium Chloride (NaCl), Potassium Chloride (KCl), etc.. If the chloride were to disassociate, it becomes chlorine. Chlorine is very unstable in solution and will degas quickly. Could this be the reason? I don't know.
Thanks
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Post by SrCusEngr on Oct 30, 2021 21:50:36 GMT
One other item of importance to understand. The machine is attempting to achieve a desired conductivity value with a given dialysate solution. The pumps pull in solutions to achieve that conductivity. It is impossible for the machine to discern one elemental value from another. It can only react to the total conductivity of the combined mixture {(acid + [bicarbonate + water]) for the final conductivity sensor and the value of the Bicarbonate (bicarbonate + water) for the bicarb conductivity sensor}.
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